Achieve Positive Wound Sampling Results Using Bacterial Fluorescence From the MolecuLight i:X™

The MolecuLight i:X excites tissue and bacteria with violet light, causing potentially harmful bacteria to produce red fluorescence. Multi-site clinical trials* have found a 100% positive predictive value (PPV) of this red fluorescence for detecting potentially harmful bacteria in wounds, regardless of sampling technique (curettage or biopsy) or microbiological analysis method (culture or qPCR).

 
MolecuLight i:X Guided Curettage Sampling
MolecuLight i:X Guided Biopsies
PPV
100%
100%
# of Patients
30
30
Microbiology
Culture
qPCR
Bacterial Loads
Predominately moderate/heavy
≥ 104 CFU/g
MolecuLight Clinical Case 0043.
* Clinicaltrials.gov registry number NCT02682069.

Pathogens Detected from Regions of Red Fluorescence

Red fluorescing Staphylococcus aureus
Red fluorescing Staphylococcus aureus

Red fluorescing Beta-hemolytic Streptococci (Group B)
Red fluorescing Beta-hemolytic Streptococci (Group B)

Red fluorescing Citrobacter koseri
Red fluorescing Citrobacter koseri

Arrow indicates sampling location.

 
Case-Study-0043-qPCR

 

Case-Study-0043-Culture