CASE STUDIES

Below are a series of case studies highlighting how the MolecuLight i:X integrates in wound care protocols and guides clinicians in their wound care practice.

Integrating the MolecuLight i:X into the debridement process allows for more effective and complete debridement by targeting regions of high bacterial load, imaging post-debridement, and repeating the treatment if necessary, to target remaining bacteria and ensuring overall faster wound closure.3,5

The MolecuLight i:X guides clinicians to sample in regions where bacteria is visualized, which leads to cost savings by improving sampling accuracy and eliminating unnecessary sampling.1,2,3,4

The MolecuLight i:X allows clinicians to focus cleaning in the areas where bacterial fluorescence is present and may have been missed by standard of care, including areas adjacent the wound or on the periphery of the wound bed, for more effective and thorough wound cleaning.8,9

Clinicians using the MolecuLight i:X have reported that they are able to make the decision NOT to use broad spectrum antibiotics and/or expensive antimicrobial dressings more confidently on patients who do not show clinical signs and symptoms of infection.3,10,20

References

[1] Interim data from 27 patients in ongoing Post Market Clinical Follow-up Study (Positive Predictive Value of the MolecuLight i:X Imaging Device to Predict the Presence of Bacteria in Chronic Wounds; MLI Study 16-101).
[2] Interim data from 16 patients in ongoing clinical trial (Positive Predictive Value of the MolecuLight i:X Imaging Device to Predict the Presence of Bacteria in Chronic Wounds; clinicaltrials.gov registry number NCT02682069).
[3] DaCosta RS, Kulbatski I, Lindvere-Teene L, Starr D, Blackmore K, Silver JI, Opoku J, Wu YC, Medeiros PJ, Xu W, et al. Point-of-care autofluorescence imaging for real-time sampling and treatment guidance of bioburden in chronic wounds: first-in-human results. PLoS One. 2015 Mar 19;10(3).
[4] Ottolino-Perry K, Chamma E, Blackmore K, Lindvere-Teene L, Starr D, Tapang K, Rosen C, Pitcher B, Panzarella T, Linden R, DaCosta RS. Improved detection of wound bacteria using fluorescence image-guided wound sampling in diabetic foot ulcers. Int Wound J. 2016 (In revisions).
[5] Landis S. Wound Mapping: A Guide to Targeted Debridement and Wound Healing. [accessed 2016 Dec 7]. http://moleculight.com/wound-mapping-guide-targeted-debridement-wound-healing-webcast/.
[6] Landis S. Mapping venous ulcers using bacterial autofluorescence to identify subgroups at risk of infection post debridement. Proceedings of the Annual Canadian Association of Wound Care Conference; 2016 Nov 3-6; Niagara Falls, ON.
[7] Landis S. Determining the effectiveness of sharp debridement using wound/periwound bacterial autofluorescence imaging. Proceedings of the Annual Symposium on Advanced Wound Care; 2016 April 13-17; Atlanta GA.
[8] Raizman R. Point-of-care bacterial fluorescence imaging device guides care and patient education in obese patients with surgical site infections. Proceedings of the Annual Canadian Association of Wound Care Conference; 2016 Nov 3-6; Niagara Falls, ON.
[9] MolecuLight. Improved cleaning with MolecuLight i:X led to successful patient outcome [Case study PN 1255]. 2016.
[10] Blumenthal E, Jeffrey S. The use of MolecuLight i:X in burn wounds. Proceedings of the Annual Australian & New Zealand Burn Association Conference; 2016 Oct 11-14; Auckland NZ.
[11] MolecuLight. Avoid unnecessary use of antimicrobial dressings with the MolecuLight i:X [Case study 0038]. 2016.
[12] MolecuLight. Track Wound Size and Bacterial Presence with the MolecuLight i:X [Case study 0051]. 2016.
[18] Improve Measurement Accuracy of Irregular Wound Borders with the MolecuLight i:X™[Case study 0018].
[19] The MolecuLight i:X Imaging Device is approved by Health Canada (Medical License #95784)
[20] Raizman R and DaCosta RS. Handheld real-time fluorescence imaging of bacteria guides treatment selection and timing of dressing changes in inpatients undergoing negative pressure wound therapy. Proceedings of the Innovations in Wound Healing Conference; 2016 Dec 8-11, Key Largo, FL.