Monitoring the Effectiveness of an Antibiotic Against MRSA with the MolecuLight i:X™

Methicillin resistant Staphylococcus aureus (MRSA) infections are difficult to treat with standard types of antibiotics and are therefore more dangerous and more costly to the healthcare system.

Clinical Synopsis: Although Negative Pressure Wound Therapy (NPWT) had significantly reduced wound size in this non-healing venous leg ulcer, all treatments targeting MRSA infection had been unsuccessful. This prompted prescription of a newly available oral antibiotic. After one week of treatment, MolecuLight i:X fluorescence images revealed a significant decrease in bioburden, providing immediate feedback on antibiotic effectiveness.

Images taken in Standard Imaging ModeTM
Image taken in Fluorescence Imaging ModeTM
(presence of bacteria indicated by red color)

Wound Etiology
  • Venous leg ulcer (> 1 year), left medial ankle
Patient Demographics
  • Male, 50 years old
Patient-Related Challenges
  • Persistent MRSA
  • Heavy drainage
Patient’s General Care Paradigm
  • NPWT and antimicrobials
  • Numerous antibiotics
Clinician Stated Utility of the MolecuLight i:X
  • Immediate feedback on effectiveness of prescribed antibiotic
Images provided by Rose Raizman RN-EC, MSc, Scarborough & Rouge Hospital, ON, Canada
MolecuLight Clinical Case 0020b.