Monitoring the Effectiveness of an Antibiotic Against MRSA with the MolecuLight i:X™

Methicillin resistant Staphylococcus aureus (MRSA) infections are difficult to treat with standard types of antibiotics and are therefore more dangerous and more costly to the healthcare system.

Clinical Synopsis: Although Negative Pressure Wound Therapy (NPWT) had significantly reduced wound size in this non-healing venous leg ulcer, all treatments targeting MRSA infection had been unsuccessful. This prompted prescription of a newly available oral antibiotic. After one week of treatment, MolecuLight i:X fluorescence images revealed a significant decrease in bioburden, providing immediate feedback on antibiotic effectiveness.

Monitoring-Antibiotic-Effectiveness-Against-MRSA-Standard-Imaging-Pic1
Monitoring-Antibiotic-Effectiveness-Against-MRSA-Fluorescence-Imaging-Pic1
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Images taken in Standard Imaging ModeTM
Monitoring-Antibiotic-Effectiveness-Against-MRSA-Fluorescence-Imaging-Pic2
Image taken in Fluorescence Imaging ModeTM
(presence of bacteria indicated by red color)

Wound Etiology
  • Venous leg ulcer (> 1 year), left medial ankle
Patient Demographics
  • Male, 50 years old
Patient-Related Challenges
  • Persistent MRSA
  • Heavy drainage
Patient’s General Care Paradigm
  • NPWT and antimicrobials
  • Numerous antibiotics
Clinician Stated Utility of the MolecuLight i:X
  • Immediate feedback on effectiveness of prescribed antibiotic
Images provided by Rose Raizman RN-EC, MSc, Scarborough & Rouge Hospital, ON, Canada
MolecuLight Clinical Case 0020b.