Wound cleansing is an essential component of wound hygiene and overall care. Clinicians have many cleansers to select from but limited information on which cleanser is most efficacious for a given patient. In this session, we learn about the benefits of scrub vs. soak, specialized wound cleansers vs. saline, and compare the efficacy of 9 common cleansers through point-of-care fluorescence imaging for detection of elevated bacterial burden (MolecuLight i:X).