Effectiveness of an Antibiotic Against MRSA Case Study

June 4, 2018 -Clinical Synopsis

Patient Condition: 50 year old male patient with a venous leg ulcer ( >1 year) on left medial ankle. Wound presented with heavy drainage and a MRSA infection that had persisted over many months of care, despite numerous antibiotics and antimicrobials. Patient’s wound received regular cleaning and debridement

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Optimizing Pseudomonas Aeruginosa Treatment Case Study

March 28, 2018 -Clinician used MolecuLight i:X to confirm the presence and location of Pseudomonas aeruginosa in a venous leg ulcer. As seen in Figure 3, the white/cyan color suggests heavy levels of Pseudomonas aeruginosa pre-debridement (the white/cyan color is due to signal oversaturation), which would otherwise be invisible to the unaided eye. The clinician uses this information to guide debridement of bioburdened tissue and re-imaged the wound post-debridement. Figure 4 indicates a reduction in bioburden post-debridement, but not the eradication of Pseudomonas aeruginosa. Read More

Efficacy of an imaging device at identifying the presence of bacteria in wounds at a plastic surgery outpatients clinic

January 1, 2018 -ABSTRACT Objective:

Current standard diagnostic practice of bacterial infections by visual inspection under white light is subjective, and microbiological sampling is suboptimal due to high false negative rates and the lengthy time needed for culture results to arrive. The MolecuLight i:X Imaging Device attempts to combat the issues faced in standard

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Point-of-care fluorescence imaging device predicts presence of pathogenic bacteria in wounds

August 2, 2017 -ABSTRACT Objective:

Bacteria in chronic wounds are invisible to the naked eye and can lead to delayed wound healing. Point-of-care bacterial fluorescence imaging illuminates a wound with 405 nm light, triggering bacteria to produce red fluorescence and enabling real-time bacterial localization. Prospective, single-blind clinical trials (clinicaltrials.gov #NCT02682069,#NCT03091361) were conducted to

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Improved detection of clinically relevant wound bacteria using autofluorescence image-guided sampling in diabetic foot ulcers

February 28, 2017 -ABSTRACT

Clinical wound assessment involves microbiological swabbing of wounds to identify and quantify bacterial species, and to determine microbial susceptibility to antibiotics. The Levine swabbing technique may be suboptimal because it samples only the wound bed, missing other diagnostically relevant areas of the wound, which may contain clinically significant bacteria.

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