

Fluorescence imaging can help the specialist in a more targeted assessment and management of infection
Fluorescence imaging can help the specialist in a more targeted assessment and management of infection
MolecuLight i:X recommended, as review of NICE guidance in new JoWC publication "Wound healing: what is the NICE guidance from the UK?" for the assessment of fluorescent bacteria in wounds.
69% of wounds had changes in treatment plans due to using the MolecuLight i:X
85% of wounds with wound bed preparation & high bacterial burden (>104 CFU/g) were impacted by information provided by the i:X
53% of wounds involving antimicrobial stewardship & high bacterial burden (>104 CFU/g) were impacted by information provided by the i:X
The Fluorescence imaging procedure was used to inform advanced wound therapies
Three cases are described in which fluorescence images provided information at the point-of-care
This information was used to guide use of antibiofilm agents, NPWT, and preparation of the wound bed for grafting
Fluorescence imaging was more accurate than clinical judgement in detecting elevated bacterial loads
$7,660 USD per patient was the estimated cost savings from using fluorescence imaging information
This information avoided the application of cellular tissue products on wounds with high levels of bacteria
9/10 wound care patients more appropriately triaged with fluorescence information
60% of these 9 patients would have been undertreated while 30% of patients were being overtreated
$1552 Single patient cost savings (USD) due to fluorescence evidence-based treatment plan changes
Wounds were assessed for CSS & fluorescence images were then acquired to determine presence of moderate-to-heavy bacterial loads
Sensitivity of fluorescence imaging was 3-fold higher than CSS (72% vs 22%; p=0.002)
Fluorescence imaging information resulted in treatment plan modifications in 73% of study wounds
Fluorescence imaging was used to screen wounds treated with split thickness grafts
These wounds were processed by MEEK/MESH technique for bacterial burden
Fluorescence imaging shows high concentrations of pathogens both in the MEEK silk layer as well as in foam linkers
This is an initial evaluation of using the MolecuLight i:X in the management of burns
The utility and efficacy of the MolecuLight i:X is evident due to the correlation between microbiology results and fluorescence images
The i:X may be able to detect bacterial load before an infection & subsequent graft failure, thereby shortening lengths of hospital stay & improving overall healing