1st study to describe healing outcomes of dehisced perineal wounds & factors associated with delayed healing
The presence of fluorescence significantly reduced the odds of wound healing in ≤ 4 weeks by 76%
Efficient, accurate diagnosis of cellulitis critical to avoid costly complications
Unique pattern of red fluorescence extending beyond the wound was observed in all cases of wound-related cellulitis
Fluorescence imaging aided in the early diagnosis of wound-related cellulitis, resulting in the initiation of oral antibiotics without delay, avoiding progressive cellulitis
Detection of Bacterial Burden, Acute Wounds
Hand trauma wounds were inspected for CSS and underwent fluorescence imaging for detection of bacterial burden
Fluorescence signals correlated with CSS and swab results in 97% of wounds
Fluorescence imaging can guide surgical debridement by providing real-time information on wounds' infected areas
88% of wounds where bacterial fluorescence was detected in peripheries (in regions not typically swabbed)
100% of pediatric patients were compliant with the MolecuLight imaging procedure
93% of clinicians who reported highest practicality of incorporating MolecuLight i:X into routine diagnostic practice
Fluorescence images for identifying bacterial loads of concern was 100% vs 63% sensitivity of CSS
Fluorescence images for identifying bacterial loads of concern was 92% compared to 82% accuracy of CSS
Fluorescence correctly identified all 8 wounds that were positive for significant bacterial growth on cultures
This is an initial evaluation of using the MolecuLight i:X in the management of burns
The utility and efficacy of the MolecuLight i:X is evident due to the correlation between microbiology results and fluorescence images
The i:X may be able to detect bacterial load before an infection & subsequent graft failure, thereby shortening lengths of hospital stay & improving overall healing
