Clinical evaluation of fluorescence imaging in positively predicting the presence of bacteria in chronic wounds at the point of care

June 1, 2018 -ABSTRACT Background:

Clinical diagnosis of infection in chronic wounds involves assessment of signs and symptoms based on visual inspection and microbiological cultures. This process is subjective and delayed culture results often prevent prompt treatment. Fluorescence imaging has recently been introduced as a new method to visualize the presence of

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Improved detection of clinically-relevant wound bacteria using autofluorescence image-guided sampling in diabetic foot ulcers

May 1, 2018 -ABSTRACT Aim:

To compare the efficacy of standard clinical signs and symptoms (CSS) guided-Levine swabbing with autofluorescence (AF) imaging-guided swabbing to detect bacteria in diabetic foot ulcers.


Twenty-nine participants with diabetic foot ulcers were recruited between December 2014 and February 2015. Diabetic foot ulcers (n=31) were evaluated for CSS

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Efficacy of an imaging device at identifying the presence of bacteria in wounds at a plastic surgery outpatients clinic

January 1, 2018 -ABSTRACT Objective:

Current standard diagnostic practice of bacterial infections by visual inspection under white light is subjective, and microbiological sampling is suboptimal due to high false negative rates and the lengthy time needed for culture results to arrive. The MolecuLight i:X Imaging Device attempts to combat the issues faced in standard

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Point-of-care fluorescence imaging device predicts presence of pathogenic bacteria in wounds

August 2, 2017 -ABSTRACT Objective:

Bacteria in chronic wounds are invisible to the naked eye and can lead to delayed wound healing. Point-of-care bacterial fluorescence imaging illuminates a wound with 405 nm light, triggering bacteria to produce red fluorescence and enabling real-time bacterial localization. Prospective, single-blind clinical trials ( #NCT02682069,#NCT03091361) were conducted to

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Improved detection of clinically relevant wound bacteria using autofluorescence image-guided sampling in diabetic foot ulcers

February 28, 2017 -ABSTRACT

Clinical wound assessment involves microbiological swabbing of wounds to identify and quantify bacterial species, and to determine microbial susceptibility to antibiotics. The Levine swabbing technique may be suboptimal because it samples only the wound bed, missing other diagnostically relevant areas of the wound, which may contain clinically significant bacteria.

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The use of the MolecuLight i:X in managing burns [Pilot Study]

January 1, 2017 -ABSTRACT

The MolecuLight i:X Imaging Device is a portable, noninvasive, real-time camera used to visualize the bacterial load in a wound. It uses violet light illumination and a dual bandpass optical filter to capture the fluorescence of endogenous structures in the tissue matrix and harmful bacteria. The MolecuLight i:X captures images

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